We are currently based in the Computational Systems Chemistry sub-section of the School of Chemistry, University of Southampton, in August of 2021 the group will be based at the Biochemistry Department, University of Oxford, with some group members also still at Southampton. Our research involves the application of a computational techniques to the study of biological membranes at the molecular level. Our bacterial cell envelope work has a particular focus on capturing the biological complexity of this key cellular architecture. We are particularly interested in the role of the membranes, cell wall and the proteins and other macromolecules that reside within the envelope in the development of antimicrobial resistance. Another key area of research is the application of knowledge gained from studying biological systems to aid the design of synthetic systems for applications in bionanotechnology, such as DNA sequencing devices through our ongoing work with Oxford Nanopore Technologies Ltd.
More recently we have also become interested in host-pathogen interactions (more details soon).
We have strong links with experimental groups in biophysics, biochemistry, chemical biology and structural biology, both in academia and industry.
Some recent news: